Fetch a pathway,
genes and drugs attached.
KEGG maps molecules onto the pathways they run in — the genes, enzymes, compounds and drugs of a biological process, wired together. kegg_search and kegg_entry return a KEGG entry pinned to its ID, so an agent can place a molecule inside the machinery it belongs to.
What the instrument does
KEGG (Kyoto Encyclopedia of Genes and Genomes) links genomic and molecular information to higher-order functions — pathway maps and the enzymes, compounds, diseases and drugs that populate them, each with a stable KEGG identifier.
On the console, kegg_search finds entries and kegg_entry fetches the full flat-file record for one — a pathway with its gene list, compounds, modules and associated drugs.
Tools this powers on the console
kegg_search · kegg_entry
Research use only. Service names belong to their owners; no partnership or endorsement is implied.
How Perslis integrates KEGG
KEGG turns an isolated molecule into a position in a process. A compound identified in PubChem or a target from ChEMBL can be placed on a KEGG pathway — glycolysis, hsa00010, with its enzyme genes, its compounds from glucose to pyruvate, and the drugs (mitapivat, etavopivat) that act on it — every element carrying a KEGG ID.
KEGG shares the pathways bench with Reactome; the two curate biological process differently, so the console offers both rather than collapsing them into one view. Every entry is pinned, so a pathway claim resolves to a KEGG record.
Ask
One question at the console — no per-service query language, no tab-hopping.
Route
Lois calls this instrument alongside the others and gathers what returns.
Pin
Every field keeps its source: database, accession, URL. A result that cannot name its source is refused by construction.
Admit
The PEEL gate decides what enters the lab record. Reported values stay verbatim; unsupported claims stay out.
A real, source-pinned result
Pulled live from the service and pinned to its identifier — the same contract every answer on the console is held to.
| Pathway | Glycolysis / Gluconeogenesis (Homo sapiens) |
|---|---|
| Class | Metabolism; Carbohydrate metabolism |
| Modules | M00001 Glycolysis, M00002 core, M00003 gluconeogenesis |
| Example compounds | C00031 D-Glucose → C00022 Pyruvate |
| Associated drugs | D11408 Mitapivat, D12362 Etavopivat |
Source: kegg · hsa00010 · retrieved 2026-09-18
Why route KEGG through one console
Context, callable
An agent places a molecule in a pathway with its genes, compounds and drugs — pinned to KEGG IDs.
Chemistry meets biology
A PubChem compound or ChEMBL target lands on the pathway it acts in — one molecule, its machinery.
Two pathway views, not one
KEGG and Reactome both answer, so their different curation is a choice the console preserves.
Instruments KEGG talks to
A pathway connects molecules to a process. KEGG answers beside Reactome and the chemistry bench.
